True Blood is an American television drama series created and produced by Alan Ball. It is based on The Southern Vampire Mysteries series of novels by Charlaine Harris, and details the co-existence of vampires and humans in Bon Temps, a fictional small Louisiana town. The series centers on Sookie Stackhouse (Anna Paquin), a telepathic waitress at a bar, who falls in love with vampire Bill Compton (Stephen Moyer).

True Blood is broadcast on the premium cable network HBO in the United States. It is produced by HBO in association with Ball's production company, Your Face Goes Here Entertainment. It premiered on September 7, 2008.

The first season received critical acclaim and won several awards, including one Golden Globe and an Emmy. The show's second 12-episode season had its premiere on June 14, 2009 and the third season on June 13, 2010. On June 21, 2010, HBO renewed True Blood for a fourth season, set to debut on June 26, 2011.